I use oils that meet the manufacturers specifications, regardless if dino or syn. One change I may go with a semi syn, the next a full syn, all depends on the upcoming workload. Either way, I use a name brand oil, for the most part Mobil 1, or Shell Rotella.
What really matters most is not the oil itself, any rated oil will do what its intended to do, but whats important is using a GOOD filter. The oil serves two purposes in an engine, Lubricate, and carry byproducts away to be filtered out. If using good oil and a cheap filter, well, why bother?
Any rated oil will lubricate properly, synthetics just happen to do it longer than Dino. So follow the basic rules, Properly Rated, of the correct viscosity and use a GOOD filter.
Back in the 90's I rebuilt a first gen 5.0 in a Ford LTD Wagon, blue printed it and used Castrol GTX 10w30 in it all the time. I put 300K on that engine which wound up in two different cars while I had it. Sometimes I would go 10-15K between changes, but always had a Motorcraft filter, and Castrol GTX in it. When I pulled it out of the LTD to drop into a Grand Marquis with 280K on it, I had to swap the pan, so for shits and giggles popped the bearing caps off a couple rods and main and plastigauged them. All bearings were smooth and all speced out the proper clearances for a new engine. There was NO buildup inside, just the normal heat varnish on the metal. It was then that I knew for a fact that 3K oil change intervals was a gimmick to sell more oil, Hello Jiffy Lube! Been doing 10K changes ever since and never have had any oil related issues on any engine. Of course I always drove for long periods, no short hops that left the engine cold and damp, always got it good and hot to burn off moisture.
Good oil, good filters, good to go.