Hogs Back exposed the 5.0's true nature to me. Flat land it was fine, but any real grade it had to sit at 4500-5000 rpms to maintain speed. Tow/Haul was cool that in would drop gears while you rode the brakes but the line of people behind me probably didnt care.
My 5.3 Tahoe with a 4 speed was a better match, but the short wheelbase and overall lighter weight made it less than ideal. Im currently deciding between a 2012 F250 with a 6.2 gasser and a 2011 2500HD with the Ol 6.0
I had a 4.6 liter f150 with the four speed auto. It handled the Bota fairly well around here. All though my GMC with the 5.3 liter does much better.
If your considering the v10 from ford, save your money. Even with the 6 speed auto it struggles in the hills. Company just bought me a new service truck with the v10. It's the f550. With just the utility bed setup it's at 12,000lbs. There's a fairly steep hill coming out of town with a stoplight at the bottom. Starting from the stoplight I can only get around 45 mph unless I pin it to the floor. Then I can get 55 mph. After filling the oil tanks and adding parts, it can only get 45 mph pinned. Add a 4500lb piece of equipment behind it and your looking at 35 mph up the hill. Plus the v10 gives a whole new meaning to the term fuel slut
Getting a whopping 6mpg in the city and 7.5 mpg highway
Same setup in a diesel gets 14 mpg city and romps up the hills with enough butt to get out of it's own way