I'm curious where you are getting your R404A. My current price for it is $7.10 per pound (weight), and I have no idea what that translates to in filling a tire, but seems expensive to me. I'm also not sure what unintended effects it might have (maybe none), but I would want to know. As for nitrogen, it's fine, but I have never seen the value of it on a street car. If you need to air up in a pinch, you either have to find somebody who has it or contaminate your nitrogen with regular air and you have to start over. I worked on NASCAR type stock cars where it is used to control air pressure build up as the car makes laps, (Increased air pressure changes the tire circumference on a bias ply tire, (stagger) and effectively changes the spring rate of the car on a radial tire.) but if your street tires are getting hot enough for that to matter, you better be fixing something. I am always leery when somebody comes up with a plan that supposedly means you don't have to check something or maintain something. I have gotten in the habit of checking my trailer tires before each trip, because no matter WHAT the tire is filled with, it COULD be sitting there with a nail in the tire just waiting to bite you when you get out on the road. I have some trailers that sitting there empty, the tires will look normal even when there is almost no air in them. You go somewhere, put a load on the trailer and find out the tire was really flat. Just some food for thought for everybody.